VIDEO TESTATA 1

UNIQUE BLEND TO SUPPORT HEALTHY MUCOSAE AND COUNTERACT GASTROESOPHAGEAL REFLUX DISEASE

PRODOTTO 2

MUCOSAVE™ FG is a blend of two herbal extract containing polysaccharides of prickle pear cladodes (Opuntia ficus indica (L.)) and biophenols of olive leaves (Olea europaea (L.)).

MUCOSAVE™ FG is a unique combination specifically created for mucosal treatment and to counteract the main symptoms caused by gastric disorders.

Gastroesophageal Disease (GERD) is a common ailmentwhich is growing in incidence on a global level. Common
symptoms include heartburn, regurgitation and nausea. There is a need for effective natural treatments without harmful side effects to address this problem. Mucosave is the innovative and natural ingredients to improve the GUT HEALTH.

APPLICAZIONI 3

Opuntia ficus-indica is the most widespread cactus into the Mediterranean lands. To survive in a dry climate, the The plant uses its “leaves” (cladodes) to save water. Under the prickly surface, the cladodes contain a juicy soft gel filled very rich in polysaccharide.

The Opuntia ficus-indica cladodes, polysaccharide-containing, are used in folk medicine for their wound- healing activities and are widely employed for the treatment of mucous membrane irritation.

Olea europaea, is a species of tree in the family Oleaceae, found in the Mediterranean Basin. The first known record of olive leaf comes from Ancient Egypt. It has since been used extensively in traditional medicine and is still popular across many cultures today.

The phenolic compounds present in olive leaves, are associated to antioxidant, and lenitive activity. The unique combination of biophenols in the olive leaf have many potential health benefits.

WHAT IT DOES

MUCOSAVE™ FG has a strong mucoadhesive ability thanks to the Opuntia polysaccharides and a lenitive effect from olive biophenols to protect the sensitive mucosae. Thanks to this combination, MUCOSAVE™ FG improves gastrointestinal disorder and counteracts gastroesophageal reflux.

STUDI SCIENTIFICI 4

SCIENTIFIC INVESTIGATIONS
OF MUCOSAVE™ FG PROTECTION

Mucobioadhesive properties has been evaluated by a new in vitro model (mucous membrane cell lines), predicting in vivo conditions. In these studies, MUCOSAVE™ FG has shown a strong mucoadhesive activity (up to 60% of cell surface), higher than other bioadhesive polymers such as hyaluronic acid and alginate (30% and 5% respectively).

Heartburn and acid regurgitation episodes per week in subjects with GER before (green) and after (orange) 60 days treatment with MUCOSAVE™ FG/alginate/bicarbonate combination (verum) or maltodextrin (placebo).

Heartburn
episodes

Acid regurgitation
episodes

70% OF REDUCTION OF THE EPISODE OF HEARTBURN AND ACID REGURGITATION*

*Gastro Esophageal Reflux Disease-Health Related Quality of Life (GERD-HRQoL) and Gastroesophageal Reflux Disease Symptom Assessment Scale (GSAS).